OPTIMISED Curcumin

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Whilst the main ingredients in our products are oils (fat), it is doubtful that they will cause weight gain.  RESTORE, Vegepa E-EPA 70, Omegaflex DUO and Orange Bursts provide between 4.5 and 6 kcal (calories) per capsule. More important, however, is that omega-3 fatty acids play a very important role in fat metabolism in the body and actually push dietary fat towards the production of energy rather than fat storage.  In other words, people are more likely to lose weight by including omega-3 in their diet.

It is very difficult to say how quickly you will notice benefits because factors such as age, weight, condition and lifestyle can all affect how quickly the fatty acids can be effectively used by the body. Of all the factors known to influence the effects of omega-3 on any one person, the most important is their baseline (or starting point!) omega-3 levels – better known as the ‘omega-3 index’.

Those individuals who have lowest omega-3 levels will need to take higher amounts and for longer than individuals with a higher omega-3 index. The simplest way to maximise the health benefits from taking one of our omega-3 supplements is by taking the Opti-O-3 fatty acid biomarker test. By providing us with a small amount of blood (a simple process that can be performed in your own home using a lancet finger-prick device included with the test kit), our laboratory will identify your current levels. Using this information in conjunction with your weight, we calculate the bespoke dose required to help raise your omega-3 levels to those associated with clinical improvements.With a personalised dose that matches your individual requirements, it takes the guesswork out of supplementation and optimises the speed with which the active ingredients start to provide noticeable benefits.

As a standard guideline however, conditions relating to mental health are often the quickest to respond, whilst those affecting the heart, energy, brain performance and cellular health may take several months. We recommend that individuals should take our products for a minimum of three months to show noticeable beneficial effects, though scientific studies show that those taking fatty acids for six months or more benefit from even greater improvement to symptoms.

The benefits of omega-3 supplementation for controlling hypertension (high blood pressure) are well established. Since the therapeutic dose required to reduce blood pressure is relatively high, we would recommend initial dosage of 4 capsules per day of RESTORE which would provide just over 2g EPA

Yes, in fact a combination of statins and EPA has been shown to reduce cholesterol levels more effectively than either substance individually. Statins, like EPA, inhibit an enzyme called HMG-CoA, which regulates the rate of cholesterol production in the body. 

EPA inhibits an enzyme called HMG-CoA, which regulates the rate of cholesterol production in the body. As with recommendations for high blood pressure, the amount of EPA needed is relatively high; we would therefore recommend 4 capsules of RESTORE per day, which would provide just over 2g EPA.

Whilst these fatty acids are both essential for good health, their structures are very similar and they compete for binding sites as well as essential enzymes. EPA and DHA are found together in most supplements, but their competitive relationship means that the anti inflammatory beneficial actions are derived from any excess EPA or DHA, once any equal quantities of EPA and DHA have effectively cancelled each other out.

Many recent clinical studies, especially those focusing on the benefits of omega-3 in inflammatory conditions, have investigated the actions of pure EPA owing to its dual protection against excess inflammation in the body: EPA displaces the omega-6 AA content of cell membranes, reducing the inflammatory products that can be produced from AA – effectively regulating inflammatory pathways – and it also enhances the production of anti-inflammatory products that are directly converted from EPA.

Supplementing the diet with pure EPA without DHA therefore maximises the beneficial actions of this important nutrient for inflammatory conditions because it is unopposed by the competing actions of DHA for binding sites and enzymes. 

Omega-3 fatty acids reduce the ‘stickiness’ of platelets (the cells that cause blood to clot), and this is known to be beneficial for cardiovascular health. Having slightly ‘thinner’ blood increases circulation and also lowers blood pressure. Individuals taking pharmaceutical blood-thinning agents such as Warfarin or Heparin should consult their GP before taking a highly concentrated fish oil supplement. 

Whilst it is generally safe to take fish oils during pregnancy, it is advisable to consult your doctor first.  A GP should be able to outline anything in your personal history that may give reason to avoid supplementation during pregnancy.   For example, pre-eclampsia, a complication of pregnancy can result in pre-term bleeding, and this could be exacerbated by the blood-thinning effects of EPA. As regards to concerns about heavy metals, our products are highly purifed to remove contaminants. Glucosamine in Omegaflex DUO should not be taken by pregnant women. 

Interestingly, people with diabetes have a reduced capacity to make long-chain fatty acids and are at a higher risk of cardiovascular and nerve problems. Supplementing with omega-3 fish oil is therefore extremely beneficial for people with diabetes, as a way of decreasing the risk of associated health problems long-term. We recommend our product Vegepa E-EPA 70 for diabetics, which contains omega-3, -6 fatty acids, for cardiovascular benefits, as well as for brain and eye health.

The heart health contraindications of calcium relate to those supplements derived from rock or limestone. Our calcium is derived from a natural food source – derived from seaweed, it is more bioavailable in the body and is readily utilised. Unfortunately, with rock-derived calcium, the body struggles to absorb this source of calcium which is therefore then free to travel around the circulation and become deposited in arterial plaque. It is this calcified arterial plaque clogging arteries that leads to an increased risk of heart attack and stroke. 

Yes, there is increasing research that implies that taking a daily fish oil supplement may boost the effectiveness of antidepressants in some people. The addition of a daily dose of omega-3 fatty acids (in particular EPA) to regular antidepressant treatment has been shown to significantly improve symptoms including anxiety, sadness, decreased sexual drive and suicidal tendencies. 

We include 1mg of soy-derived vitamin E in each capsule of Vegepa E-EPA 70, Vegepa Orange Bursts and Omegaflex DUO and 5mg in RESTORE to protect the oil from oxidation (and turning rancid). However, during the manufacturing process, all protein materials are removed and the final product is therefore non-allergenic.

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